Synthesis and Antimicrobial Studies of Some Novel Pyrazoline and Isoxazoline Derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis and estimations of antimicrobial properties of novel pyrazoline derivatives
Chalcones are the condensation product of acetophenone in combination with aromatic aldehydes in the presence of strong base. Chalcones and their metal complexes having prominent role in modern coordination chemistry. These compounds possessing novel structural features, interesting spectral and magnetic properties, have been the subject of intensive research due to their importance in medical,...
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15 صفحه اولVolume: I: Issue-3: Nov-dec -2010 Issn 0976-4550 Synthesis and Antimicrobial Studies of Some Novel Isoxazoline Derivatives
In the present investigation, a series of novel isoxazoline derivatives 4a-i were synthesized by cyclization of 1-(2’-hydroxy phenyl)-5-(6’’-methoxynaphthalen)-2-propene-1-one (i.e. Chalcones) 3a-i with hydroxylamine hydrochloride in dimethyl formamide and sodium acetate to obtained 3-(2’-hydroxy phenyl)-5-(6’’-methoxynaphthalen)-2-isoxazolines 4a-i. The structures of newly synthesized compound...
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Some new [3-(4-phenyl)-5-phenyl-4,5-dihydropyrazol-1-yl](pyridine-4-yl)methanones and 3-substituted phenyl-5-substituted phenyl-4,5-dihydro-pyrazole-1-carbothioamides have been synthesized employing microwave techniques and evaluated for antimicrobial activity. Substituted acetophenones (1) were reacted with appropriately substituted benzaldehydes (2) in the presence of ethanol to furnish subst...
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Alguns novos derivados de pirazol-5-carbonitrila 8,9 e pirazol-5-carboxamida 13 foram sintetizados pela reação de cicloadição de nitriliminas 3,4 a α-cianocinamonitrilas 5a-f e α-cianocinamamida 12a,b, respectivamente. Por outro lado, a adição de 3,4 a α-cianocinamato de etila 14a-f leva à produção de derivados de 2-pyrazoline-5-carboxilato de etila, 15, 16. Também, a cicloadição de 3,4 à 3-cia...
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ژورنال
عنوان ژورنال: E-Journal of Chemistry
سال: 2009
ISSN: 0973-4945,2090-9810
DOI: 10.1155/2009/361564